Marketing Executive ? Online Publishing, International Brand ...

Agile Talent Management Limited ? Central London ? in a growing business where reward is linked to results. This is an exciting and varied role with superb career prospects, so apply now! Key words: Online Marketing Executive, Online Publishing, subscriptions, International Publishing, Offline, SEO, Organic Search, PPC, pay-per-click, web analytics, mobile marketing, mobile apps, social media marketing, email marketing, affiliate, display, advertising, online search, traditional, subscription marketing, content management, keywords, banner?Marketing Executive ? Online Publishing, International Brand ? London ? Maternity Cover (9-12 Months) c?22.5k Basic + 25% Commission paid monthly ? OTE of ?28k+, plus StrongBenefits! Superb opportunity to join this leading FTSE 250 International Financial Publishing & Media brand based in central London as a Marketing Executive, helping to develop and deliver exciting online & offline marketing strategies to grow revenues across their portfolio of titles.

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Marketing Executive ? Online Publishing, International Brand ? London ? Maternity Cover

Source: http://www.jobsinlondon.co.in/jobs/management-executive/marketing-executive-%E2%80%93-online-publishing-international-brand-%E2%80%93-london-maternity-cover

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Is political text message spam legal? (Los Angeles Times)

Share With Friends: | | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/251212188?client_source=feed&format=rss

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Georgian police arrest opposition-linked suspects

TBILISI, Georgia (AP) ? Georgia's government accused the opposition on Monday of attempting to bribe police officers amid a prison abuse scandal that has heightened tensions in the ex-Soviet nation ahead of a fiercely contested parliamentary election next week.

The Interior Ministry said four opposition-linked suspects have been arrested. It said the suspects are linked to a candidate of the opposition Georgian Dream coalition that is challenging President Mikhail Saakashvili's party in the Oct. 1 vote.

The ministry alleged that the opposition tried to bribe police officers to resign in protest over the prison abuse scandal in order to increase pressure on the government.

The opposition dismissed the claims as a "fraudulent provocation."

"Lies and violence have been the main weapons of Saakashvili's government in the fight against political opponents and the Georgian people," it said in a statement. "An end to this violent policy will be put on Oct. 1."

Support for Saakashvili's party has been dented by graphic videos showing guards in the ex-Soviet nation brutally beating prisoners and raping them with truncheons and broom handles. Saakashvili has accused his main rival, billionaire philanthropist Bidzina Ivanishvili, of timing the release of the videos to the election ? the allegations Ivanishvili has denied.

An opposition victory in the vote would make Ivanishvili Georgia's prime minister and Georgia's No. 1 leader starting next year when Saakashvili's second and final term ends, thanks to a political reform that will shift powers from the presidency to the parliament and the prime minister.

Saakashvili has sought to contain the damage by firing Interior Minister Bacho Akhalaya and the minister in charge of the penitentiary system. He also has completely reshuffled prison personnel, suspending all former guards and replacing them with regular police.

Despite his efforts to curtail public anger, students, who spearheaded last week's protests, returned to the streets of Tbilisi on Monday to continue pushing for Akhalaya to be prosecuted.

They also are demanding the dismissal of the justice minister.

Source: http://news.yahoo.com/georgian-police-arrest-opposition-linked-suspects-182513359.html

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Alternative YouTube app for iPad

With the introduction of next version of Apple?s mobile operating system, iOS 6, Apple has marked the departure of Google?s influence in iOS. There?s no more YouTube app and the Google Maps app has been replaced by Apple?s own Apple Maps.
YouTube app has been mainstay of iOS home screen since the launch of first iPhone. This is what Apple replied The Verge when asked about the reason behind the removal of iconic YouTube app:

?Our license to include the YouTube app in iOS has ended, customers can use YouTube in the Safari browser and Google is working on a new YouTube app to be on the App Store.?

With the Youtube app out of the scene, other app developers are launching their own applications in order to fill the void. Also, departure of YouTube app is a great news for developers as they can create their own YouTube app and yet not be a ?duplicate iOS functionality?. Google is still offering a Youtube app to download, but it?s restricted only to iPhone users, so iPad users are pretty much helpless as of now, but fret not because there are few great YouTube apps already. One such app is Jasmine. Jasmine is a YouTube app that is compatible with both, iPhone and iPad. It?s the best option out there for iPad users, and perhaps it?s better than what Google was offering until now. Jasmine is the brainchild of Jason Morrissey, and he is popular for developing the Alien Blue Reddit app for iOS, which happened to be so user friendly that it was declared as the official Reddit client.

Jasmine is capable of doing most of the tasks you would have ever wanted in a YouTube app. Of course it allows you to perform basic tasks such as search/browse for videos, access your playlists, viewing history, favorite videos, and subscriptions. In addition to all those, you can also toggle between night/day mode easily, and control appearance, video playback, parental controls among many other settings.

Jasmine is available for free from the App Store over here. Also, it is iPhone 5 ready, so it has been designed for the new resolution and hence it won?t be letterboxed. This app is perhaps the best solution for iPad users until Google launches its own app.

Lack of Google stuff in iOS 6 has been pretty embarrassing for Apple. Apple has replaced the default mapping app from Google Maps to Apple Maps, which means users are basically forced to switch the app they use. People have been reporting various problems with iOS 6 Apple Maps. For the new mapping app, Apple has teamed up with Tom Tom for their data set, which is a bit weak when compared to what Google is equipped with. After all these criticism, TomTom has responded saying that it just responsible for ?foundation? of Apple Maps and has no hands in deciding the final user experience. That?s a reasonable explanation as Apple?s mistakes can cause a loss for TomTom, besides TomTom has its own iOS app which does its job perfectly fine.

What are your thoughts on Apple?s decision? Let us know using the comment form below.

Tags: apps, jasmine, Youtube

Category: Apple

Source: http://thedroidguy.com/2012/09/alternative-youtube-app-for-ipad/?utm_source=rss&utm_medium=rss&utm_campaign=alternative-youtube-app-for-ipad

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Ranker: Draft the best players and compete with your own dream team with these top NBA 2K13 players. http://t.co/lPNWGnk6

Sorry, Readability was unable to parse this page for content.

Source: http://twitter.com/Ranker/statuses/249632162528231425

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"Homeland" taps F. Murray Abraham for recurring role

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Jesus's wife? Scholar announces existence of a new early Christian gospel from Egypt

ScienceDaily (Sep. 18, 2012) ? Four words on a previously unknown papyrus fragment provide the first evidence that some early Christians believed Jesus had been married, Harvard Professor Karen King told the 10th International Congress of Coptic Studies today.

King, the Hollis Professor of Divinity at Harvard Divinity School, announced the existence of the ancient text at the Congress's meeting, held every four years and hosted this year by the Vatican's Institutum Patristicum Augustinianum in Rome. The four words that appear on the fragment translate to, "Jesus said to them, my wife." The words, written in Coptic, a language of ancient Egyptian Christians, are on a papyrus fragment of about one and a half inches by three inches.

"Christian tradition has long held that Jesus was not married, even though no reliable historical evidence exists to support that claim," King said. "This new gospel doesn't prove that Jesus was married, but it tells us that the whole question only came up as part of vociferous debates about sexuality and marriage. From the very beginning, Christians disagreed about whether it was better not to marry, but it was over a century after Jesus's death before they began appealing to Jesus's marital status to support their positions."

Roger Bagnall, director of the Institute for the Study of the Ancient World in New York, believes the fragment to be authentic based on examination of the papyrus and the handwriting, and Ariel Shisha-Halevy, a Coptic expert at Hebrew University in Jerusalem, considers it likely to be authentic on the basis of language and grammar, King said. Final judgment on the fragment, King said, depends on further examination by colleagues and further testing, especially of the chemical composition of the ink.

One side of the fragment contains eight incomplete lines of handwriting, while the other side is badly damaged and the ink so faded that only three words and a few individual letters are still visible, even with infrared photography and computer photo enhancement. Despite its tiny size and poor condition, King said, the fragment provides tantalizing glimpses into issues about family, discipleship, and marriage that concerned ancient Christians.

King and colleague AnneMarie Luijendijk, an associate professor of religion at Princeton University, believe that the fragment is part of a newly discovered gospel. Their analysis of the fragment is scheduled for publication in the January 2013 issue of Harvard Theological Review, a peer-reviewed journal.

King has posted a draft of the paper, an extensive question-and-answer on the fragment and its meaning, and images of it, on a page on the Divinity School website.

The brownish-yellow, tattered fragment belongs to an anonymous private collector who contacted King to help translate and analyze it. The collector provided King with a letter from the early 1980s indicating that Professor Gerhard Fecht from the faculty of Egyptology at the Free University in Berlin believed it to be evidence for a possible marriage of Jesus.

King said that when the owner first contacted her about the papyrus, in 2010, "I didn't believe it was authentic and told him I wasn't interested." But the owner was persistent, so in December 2011, King invited him to bring it to her at Harvard. After examining it, in March 2012 King carried the fragment to New York and, together with Luijendijk, took it to Bagnall to be authenticated. When Bagnall's examination of the handwriting, ways that the ink had penetrated and interacted with the papyrus, and other factors, confirmed its likely authenticity, work on the analysis and interpretation of the fragment began in earnest, King said.

Little is known about the discovery of the fragment, but it is believed to have come from Egypt because it is written in Coptic, the form of the Egyptian language used by Christians there during the Roman imperial period. Luijendijk suggested that "a fragment this damaged probably came from an ancient garbage heap like all of the earliest scraps of the New Testament." Since there is writing on both sides of the fragment, it clearly belongs to an ancient book, or codex, not a scroll, she said.

The gospel of which the fragment is but a small part, which King and Luijendijk have named the Gospel of Jesus's Wife for reference purposes, was probably originally written in Greek, the two professors said, and only later translated into Coptic for use among congregations of Coptic-speaking Christians. King dated the time it was written to the second half of the second century because it shows close connections to other newly discovered gospels written at that time, especially the Gospel of Thomas, the Gospel of Mary, and the Gospel of Philip.

Like those gospels, it was probably ascribed to one or more of Jesus's closest followers, but the actual author would have remained unknown even if more of it had survived. As it stands, the remaining piece is too small to tell us anything more about who may have composed, read, or circulated the new gospel, King said.

The main topic of the dialogue between Jesus and his disciples is one that deeply concerned early Christians, who were asked to put loyalty to Jesus before their natal families, as the New Testament gospels show. Christians were talking about themselves as a family, with God the father, his son Jesus, and members as brothers and sisters. Twice in the tiny fragment, Jesus speaks of his mother and once of his wife -- one of whom is identified as "Mary." The disciples discuss whether Mary is worthy, and Jesus states that "she can be my disciple." Although less clear, it may be that by portraying Jesus as married, the Gospel of Jesus's Wife conveys a positive theological message about marriage and sexuality, perhaps similar to the Gospel of Philip's view that pure marriage can be an image of divine unity and creativity.

From the very beginning, Christians disagreed about whether they should marry or be celibate. But, King notes, it was not until around 200 that there is the earliest extant claim that Jesus did not marry, recorded by Clement of Alexandria. He wrote of Christians who claimed that marriage is fornication instituted by the devil, and says people should emulate Jesus in not marrying, King said. A decade or two later, she said, Tertullian of Carthage in North Africa declared that Jesus was "entirely unmarried," and Christians should aim for a similar condition. Yet Tertullian did not condemn sexual relations altogether, allowing for one marriage, although he denounced not only divorce, but even remarriage for widows and widowers as overindulgence. Nearly a century earlier, the New Testament letter of 1 Timothy had warned that people who forbid marriage are following the "doctrines of demons," although it didn't claim Jesus was married to support that point.

In the end, the view that dominated would claim celibacy as the highest form of Christian sexual virtue, while conceding marriage for the sake of reproduction alone. The Gospel of Jesus's Wife, if it was originally written in the late second century, suggests that the whole question of Jesus's marital status only came up over a century after Jesus died as part of vociferous debates about sexuality and marriage, King said. King noted that contemporary debates over celibate clergy, the roles of women, sexuality, and marriage demonstrate that the issues are far from resolved.

"The discovery of this new gospel," King said, "offers an occasion to rethink what we thought we knew by asking what role claims about Jesus's marital status played historically in early Christian controversies over marriage, celibacy, and family. Christian tradition preserved only those voices that claimed Jesus never married. The Gospel of Jesus's Wife now shows that some Christians thought otherwise."

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The above story is reprinted from materials provided by Harvard Divinity School. The original article was written by B. D. Colen, Harvard News Office.

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Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/869ysAwmt8A/120918163643.htm

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Dan Duryea Central: Dan Duryea and Family at Home

Since this is a nice Sunday afternoon, I thought that it would be pretty fun to post a couple of pictures of Dan Duryea and his family relaxing on an afternoon and evening in their home.

The Time: 1946
(between Dan's films Black Angel and White Tie and Tails)
The Place: 7621 Mulholland Drive, Hollywood, California.

Dan D. and his wife, Helen, moved out to Hollywood when their two sons, Peter and Dick, were still very young. The Duryeas bought a two-storied Mediterranean-style house on Mulholland Drive (a highway bisecting Hollywood and the San Fernando Valley). I've included the original captions below each of the photographs.

Just click on the picture to download it full size.

After dinner the Duryeas lounge in the living room which is spacious and livable. Antiques and extravagance are conspicuous by their absence. The room is the kind that the youngsters can enjoy, and even the dogs feel at home.

Just click on the picture to download it full size.

Dan stretches out before the den fireplace to study his script of Black Angel, which was before the cameras when these shots were made. A serious actor and a good "study," he has little trouble memorizing his lines.

I've got quite a few more photos of Dan D. at home with his wife and sons, so keep checking back. Also feel free to contact me if you are looking for anything in particular! (Click on any of the tabs at the top of this page to find contact info.)

Source: http://danduryeacentral.blogspot.com/2012/09/dan-duryea-and-family-at-home.html

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Crows' brains are a lot like ours

Crows don't forget a face ? and they hold grudges, too.

Researchers in Seattle revealed last year that captured crows remember the face of their abductor. Even though years had passed since they saw the threatening face, the crows in the experiment would taunt their captor and dive-bomb him, suggesting the birds held tightly to a negative association.

Now the researchers' follow-up study shows that the birds' brains light up much like the human mind when they see a face they know.

"The regions of the crow brain that work together are not unlike those that work together in mammals, including humans," lead researcher John Marzluff of the University of Washington said in a statement from the school. "These regions were suspected to work in birds but not documented until now."

1. Science news from NBCNews.com

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In the study, 12 male adult crows were captured by researchers who were all wearing one type of mask, referred to in the study as the threatening face. Then during four weeks of captivity, the birds were fed by people wearing a different mask. Though both disguises had neutral expressions, this mask was referred to as the caring face.

To see what was going on in the birds' brains when they saw both faces, the researchers injected a glucose fluid into the bodies of fully alert crows. The crows were then put in the presence of someone wearing either the threatening or caring mask for about 15 minutes before the birds were sedated and given a brain scan. [ Pretty Bird: Images of a Clever Parrot ]

The fluid revealed which parts of their brains were most active around a certain mask-wearer. Marzluff said it appears the smart birds have a region of their brain that is analogous to the amygdala of mammals.

"The amygdala is the region of the vertebrate brain where negative associations are stored as memories," he said in the statement. "Previous work primarily concerned its function in mammals, while our work shows that a similar system is at work in birds."

The study, detailed this week in the Proceedings of the National Academy of Sciences, suggests that caretakers might be able to reduce the stress of captive animals by treating them well and consistently.

"By feeding and caring for birds in captivity, their brain activity suggests that the birds view their keepers as valued social partners, rather than animals that must be feared," Marzluff said.

He added that the findings might even be used to make better behaved crows, suggesting that the birds could be manipulated to associate eating a rare species with a negative experience to train them to avoid a particular prey.

Follow LiveScience on Twitter @livescience. We're also on Facebook? and Google+.

? 2012 LiveScience.com. All rights reserved.

Source: http://www.msnbc.msn.com/id/49005841/ns/technology_and_science-science/

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Majesco shares down after 3Q earnings miss

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Source: http://news.yahoo.com/majesco-shares-down-3q-earnings-miss-170143568--finance.html

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What You Probably Don't Know About Uterine Cancer | dailyRx

dailyRx News recently had the privilege of visiting with some of the nation?s leading specialists in various types of cancers at The University of Texas MD Anderson Cancer Center in Houston.

We talked with these oncologists about their specialties. We asked about their patients, the disease, its symptoms and the best way patients can take care of themselves after diagnosis.

We also asked what these leaders think ordinary folks should know about the cancers they?ve spent years studying and treating.

The first in this series is a conversation we had with Pamela T. Soliman, MD about uterine, also known as endometrial cancer. This is the most common female reproductive cancer that's diagnosed in some 47,000 American women every year. .

Dr. Soliman is assistant professor in the Department of Gynecologic Oncology at MD Anderson Cancer Center, where she provides both medical and surgical care to women with gynecologic cancers.

dailyRx: Dr. Soliman, tell us about your patients.

Dr. Soliman: With endometrial cancer patients, we?ve actually seen more and more younger patients. I?ve seen patients as early as their late twenties, and then obviously it goes up to even patients in their 70s and 80s. The average age for diagnosis is around sixty.

dailyRx: Why do you think you?re seeing more younger patients?

Dr. Soliman: I think probably the biggest risk factor for any endometrial cancer is obesity. Especially over the last 10 years, the incidence of obesity has really increased, and I think it has affected younger generations too. So we think, although we don?t know, that obesity has a lot to do with why we are seeing younger women with endometrial cancer.

dailyRx: What are the screening guidelines for endometrial cancer?

Dr. Soliman: There aren?t screenings for endometrial cancer. ?It?s just more awareness of abnormal symptoms.

You know, the one misconception is that PAP smear is a screening test for uterine cancer, and it?s NOT. It?s just a screening for cervical cancer. So really, we rely on patients who have abnormal symptoms to contact their doctor and be evaluated.

dailyRx: What are the signs of this cancer that shouldn?t be ignored?

Dr. Soliman: One thing about endometrial cancer is that there are actually relatively obvious signs. In women that have gone through menopause, if they have any vaginal bleeding, that?s something that should be assessed by their doctor - even if there?s just a little bit.

For women who have not gone through menopause, if they notice that their period has changed so that they are a lot heavier or if they have bleeding in between their periods, those are all symptoms that should be evaluated by a physician.

dailyRx: What is typical treatment for uterine cancer?

Dr. Soliman: It usually starts with surgery, so a hysterectomy. We usually remove the fallopian tubes and ovaries at the same time. Then, depending on where the cancer is located, we may also remove lymph nodes in the pelvis and the abdomen.

Based on the information gathered during surgery, we then decide if patients need radiation and/or chemotherapy after surgery. Depending on the type of cancer, additional treatment is required by up to 25 percent of patients.

dailyRx: When a woman is diagnosed with endometrial cancer, what?s the best thing for her to do?

Dr. Soliman: One thing that is very important is for patients to have their surgery performed by an oncologist. General gynecologists do hysterectomies all the time for other problems.

But if they have a cancer and they need to have lymph nodes removed and things like that, a general gynecologist generally would not be able to offer that.

What we try to do is let the patient have only one surgery. So, at the time of surgery, we would do the hysterectomy and remove the lymph nodes, if needed.

If they have the surgery by a general gynecologist, then they would potentially get under-treated, or when referred, would need another surgery. So, I think one thing to stress is that someone who is diagnosed with a cancer should really be evaluated by an oncologist before having surgery.

So treating endometrial cancer isn?t just about having a hysterectomy. We see people from smaller towns who come to us after having had a hysterectomy ? but it?s not the same surgery.

dailyRx: Even if a patient is seen at a cancer center, they can still be under the care of somebody else back home ? right?

Dr. Soliman: Oh yeah, absolutely! We have a lot of patients who will even come and have surgery here, and then follow-up with their doctor at home or do some kind of combined follow-up. So, we definitely work with a lot of the doctors outside of the institution for follow-up patient care.

dailyRx: How can a woman who wants to have children protect her fertility before or during treatment?

Dr. Soliman: It depends on the actual type of endometrial cancer she has. There are what we call fertility sparing types of treatments. There are also anti-hormone treatments or progesterone treatments.

We actually have a study now looking at progesterone IUD (intrauterine device) to treat early cancers so that potentially people can have kids in the future. So there definitely are options in particular patients.

dailyRx: What?s new in terms of treatment and research?

Dr. Soliman: There are a couple of things that we have going on for treatment. One is, we?re looking at different kinds of imaging and lab studies to help predict which patients are at higher risk for cancer spread at the time of surgery.

We?re going to look at CT (computerized tomography) scans and lymph node mapping, as well as some molecular markers to see if we can predict which patients are at higher risk for the spread to the lymph nodes at the time of surgery. A couple of those studies should be open by the end of the year.

Also, researchers are currently looking at new treatments or new combination treatments of medications for treating recurrent endometrial cancers.

dailyRx: What do you want our readers to know about endometrial cancer?

Dr. Soliman: Well, the first most important thing is for people to understand that obesity is a risk factor for endometrial cancer. I got my Masters in Public Health, and my thesis was actually looking at patient knowledge about obesity and cancer risks.

What we found was that less than half of women - primarily college educated women - ?had no idea that obesity increased risks for cancer, in particular endometrial cancer.

So, I think we really want to stress awareness that weight can contribute to cancer risks.?

Women should also know that Pap smears do not screen for endometrial cancer ? only cervical cancer. In fact, there are no screening tests for this type of cancer.

The other thing to know is what the signs and symptoms are. So if they have either abnormally painful periods, bleeding in between their periods or post-menopausal bleeding, they should let their doctor know because it would require further evaluation.

And finally, if they are diagnosed with endometrial cancer, they should visit an oncologist prior to getting treatment.

dailyRx News extends our thanks to Dr. Soliman for taking the time to share her expertise with us.

Source: http://www.dailyrx.com/md-anderson-oncologist-talks-about-endometrial-cancer

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Obama maintains post-convention lead over Romney: Reuters/Ipsos poll

WASHINGTON (Reuters) - President Barack Obama remained ahead of Republican presidential challenger Mitt Romney in a Reuters/Ipsos poll released on Sunday, maintaining a boost in popularity that followed the Democratic National Convention.

Of the 1,419 likely voters polled online over the previous four days, 47 percent said they would vote for Obama and 43 percent for Romney if the November 6 U.S. election were held today.

The president's margin over Romney in the daily rolling poll was unchanged from Saturday's numbers, turning up the heat on Republican strategists who were hoping for a more muted post-convention "bounce" for Obama in the wake of Friday's release of weak employment numbers.

"It means (Democrats) are on good footing going into the rest of the election," Ipsos pollster Julia Clark said.

Obama's lead already was more sustained than a smaller and shorter-lived boost that Romney enjoyed after the Republican convention finished in Tampa, Florida on August 30, Clark said. The Democratic convention ran through Thursday night in Charlotte, North Carolina.

"The task is now to stay on the message as we're still quite a ways away from the election," Clark said, reiterating her prediction that the gap in poll numbers between Obama and Romney is likely to narrow and stay close up to November 6.

Senior advisers to Romney rejected the idea that they would panic after several polls showed the former Massachusetts governor losing in key swing states, saying such results reflected the recent Democratic convention and not the ongoing tight race.

"An incumbent president who is below 50 percent in the polls is in a very bad place," one senior Romney adviser said.

Another adviser said, "if we're at 47-45 (with Obama leading) going into the Thursday before the election, I'd be very comfortable we'd win."

DIRECTION OF JOBS, ECONOMY

What Romney advisers are banking on is Americans' feelings about Obama's handling of the U.S. economy.

"Mitt has improved his standing in battleground states and is positioned perfectly on the issue of the economy with swing voters, who are so down on President Obama's performance in office," the first senior adviser to Romney said.

Sunday's Reuters/Ipsos poll showed Romney leading in popularity among registered independent voters, with 35 percent of them saying they would vote for him. Obama had 31 percent.

But asked which of the two "will protect American jobs," 32 percent of independent registered voters picked Obama, while 27 percent sided with Romney, according to Sunday's results.

Among all the 1,660 registered voters surveyed, Obama scored 42 percent compared to Romney's 35 percent.

Obama's ranking in that category has climbed steadily over the past two weeks of the daily poll, starting with 34 percent on August 28, reaching 40 percent on September 7 and peaking Sunday.

"The public view of the economy is much more about personal perception than reality," Clark said, explaining that few people pay close attention to numbers or statistics. "The fact that the dialogue is in the public sphere and Obama has been defending his record, it's possible a little bit of that is sticking."

At the same time, 72 percent of registered voters surveyed said the national economy and national deficit were on the wrong track, while 66 percent said the same about jobs and unemployment and 57 percent about the direction of things in the country in general, according to Sunday's poll numbers.

Asked how they felt about Obama, 54 percent of registered voters were favorable. Romney's favorability trailed at 49 percent.

Sunday's findings wrap up a series of daily rolling polls aimed at gauging sentiment during the two weeks of party conventions. For the survey, a sample of registered voters was interviewed online from September 5-9.

The precision of Reuters/Ipsos online polls is measured using a credibility interval. In this case, the poll has a credibility interval of plus or minus 2.7 percentage points for all respondents.

(Additional reporting by Sam Youngman in Boston; Editing by Alistair Bell)

Source: http://news.yahoo.com/obama-maintains-post-convention-lead-over-romney-054658920.html

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Uncovering the genome's regulatory code

ScienceDaily (Sep. 9, 2012) ? Since the sequencing of the human genome in 2001, all our genes -- around 20,000 in total -- have been identified. But much is still unknown -- for instance where and when each is active. Next to each gene sits a short DNA segment, and the activity of this regulatory segment determines whether the gene will be turned on, where and how strongly. These short regulatory segments are as -- if not more -- important than the genes, themselves. Indeed, 90% of the mutations that cause disease occur in these regulatory areas. They are responsible for the proper development of tissues and organs, determining, for instance, that eye cells -- and only eye cells -- contain light receptors, while only pancreatic cells function to produce insulin.

Clearly, a deeper understanding of this regulatory system -- its mechanisms and possibilities for malfunction -- may lead to advances in biomedical research, especially in developing targeted therapies for individual patients.

In spite of their importance, the "regulatory code" is not well understood. To address this problem, a research team led by Dr. Ido Amit of the Weizmann Institute Immunology Department, together with scientists from the Broad Institute in Massachusetts, including Manuel Garber, Nir Yosef and Aviv Regev, and Nir Friedman of the Hebrew University of Jerusalem, developed an advanced, automated system for mapping these sites, and then used this system to uncover important principles how these regulatory elements function. Among other things, their study, which appeared in Molecular Cell, revealed a hierarchical structure for the regulatory code. By mapping a large number of regulatory factors, the team succeeded in revealing an overall plan for gene regulation as well as the intimate details of the mechanisms involved in the immune response.

"We are seeing a race to map the regulatory code and uncover its ties to disease and human variation that is reminiscent of the race to sequence the human genome," says Amit. "But until now, participants have faced a serious hurdle: The process used for the past 30 years to map regulatory elements has been complicated, complex and labor-intensive, requiring huge scientific consortiums. With the new method, just a handful of researchers were able to conduct a study on a similar scale to the mega-team ones, and in a fraction of the time."

Their highly efficient, automated method enabled Amit and his team to measure a large number of regulatory proteins and their binding sites in parallel. They exposed immune cells to bacteria -- setting the stage for gene activation -- and then traced the actions of several dozen different regulatory proteins known to play a role in the immune response over four points in time. Not only were the researchers able to identify the binding locations of each and the genes they activate, but the levels of activation and the mechanisms employed.

One of their more significant findings was that the actions of these regulatory factors can be neatly classified into three levels in a sort of regulatory hierarchy. In the bottom tier are those factors that create the rough divisions into main cell types by directing cell differentiation. These factors are the "basic identity" guides that can, on their own, determine whether a cell will have the characteristics of a muscle cell, a nerve cell, etc. On the second tier are the regulatory factors that determine a cell's sub-identity, which they do by controlling the strength of a gene's expression. These factors are in charge of producing closely-related sub-types, for instance, muscle fibers that are either smooth or striated, or closely-related immune cells. Regulatory factors in the third tier are even more specialized: They only affect the expression of certain genes that are called into action in response to signals from outside the cell -- bacterial invaders, hormones, hunger pangs, etc.

The hope is that understanding the ins and outs of the regulatory code will help researchers to understand and predict how diseases arise and progress due to malfunctions in regulatory mechanisms. In the future, understanding the regulatory program may lead to advances in rehabilitative medicine. Regulatory mechanisms could be used to redirect the differentiation of a patient's cells, which could then be reimplanted, thus avoiding the problems inherent in using donor cells.

Amit: "The new method for mapping the gene's regulatory plan may open new vistas for investigating all sorts of biological processes, including the system failures that occur in disease."

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---

Story Source:

The above story is reprinted from materials provided by Weizmann Institute of Science.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Manuel Garber, Nir Yosef, Alon Goren, Raktima Raychowdhury, Anne Thielke, Mitchell Guttman, James Robinson, Brian Minie, Nicolas Chevrier, Zohar Itzhaki, Ronnie Blecher-Gonen, Chamutal Bornstein, Daniela Amann-Zalcenstein, Assaf Weiner, Dennis Friedrich, James Meldrim, Oren Ram, Christine Cheng, Andreas Gnirke, Sheila Fisher, Nir Friedman, Bang Wong, Bradley?E. Bernstein, Chad Nusbaum, Nir Hacohen, Aviv Regev, Ido Amit. A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals. Molecular Cell, 2012; DOI: 10.1016/j.molcel.2012.07.030

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/Fc6p-29_YF0/120910111953.htm

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Mortgage Rates

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3.250% APR 3.371%

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Rates, points and programs cannot be guaranteed on this web site because rates, fees, APR, and other costs are subject to individual borrower's credit score, loan-to-value, loan purpose, loan amount, and rapid fluctuations in market conditions.

Maximum Loan amount for a conforming loan is $417,000. Loan amounts in excess of $417,000 are considered Jumbo Conforming Loans in most Counties. Rates and APR's are based on amounts of $300,000 for Conforming Loans and $625,500 for Jumbo Conforming Loans. This is not an advertisement for credit as defined by paragraph 226.24 of regulation Z.

Source: http://yourrealestatelife.com/blog/2012/09/06/41-mortgage-rates

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What Product Announcement Are You Most Excited for This Week? [Chatroom]

There may be an Apple event rumored for next week, but this week's scheduled events might actually be even more exciting. Nokia is holding an event to unveil its rumored flagship Windows Phone 8 device, Motorola has some new announcements up its sleeve, and, of course, Amazon is expected to roll out its new line of Kindle ereaders and tablets. So the question is, what are you most excited for? More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/OEird5A_oXc/what-product-announcement-are-you-most-excited-for-this-week

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New Concepts In Construction And Real-Estate | INFORMIV ...

With the past-paced demands of a globalized world, there is no dearth of construction projects even in a developing country like ours, where the real-estate market shows a challenging flux that needs to be exploited timely and skillfully by builders, construction team heads , and the associated industry, so that a project at hand can be a profitable and viable execution.

This necessitates the active planning and a premeditated work schedule, so that architects do not lose out on meticulous details that are organized and designed accurately as per their creative concepts and technical strategies, before the project begins in reality. A mishmash of architechtural, structural and MEP services is what defines the arena of BIM, which pertains to digital 4D Model structure design that frameworks and guides an actual on-field project. From the very idea, to the bringing out of it and facilitating a convenient program, so that it becomes a cost-effective and swiftly progressive endeavor where the vision of planners co-ordinate with the objective and vision of the architect, resulting in the greatest buildings that the community can look back on as a testimony to our culture and heritage is what is connoted significantly by BIM.

India is in the midst of the phase of the real-estate and architectural boom as is China, where the most innovative concepts and building designs are on the rise.Timescale and funds are imperative and pivotal in this domain and BIM enhances the prospects on these lines by incorporating expedient team of potent engineers who work in accord with world wide standards and the state of the art system using softwares like Revit Architecture, Revit Structures, Revit MEP, Tekla and Archicad.Such innovation and advancement in a consruction stratagem alleviates the worries of design-build firms and sub-contractors.

The Building Life Cycle Management is what pushes into a demand for BIM where long term projects can be commenced even before you actually figure out a complete outline. The Beijing Airport is an exemplary point out in this regard, the largest airport in the world which runs some miles. Keeping up the so-ordination unity and integrity of an architectural design would certainly find the use of BIM indispensable .Be it in any sector, making museums, universities and corporate skyscrapers would suffer compromisingly had it not been for concepts like BIM that tackle the perfect synchronization between a dream and a pragmatic venture.

Source: http://blog.informiv.com/2012/09/new-concepts-in-construction-and-real-estate/

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Zuck: I Won't Sell Facebook Shares for a Year

Some investors and Facebook insiders may be rushing to sell off their stock in the company, but at least one person plans to hold onto his shares for a while: Facebook's CEO and cofounder Mark Zuckerberg.

[More from Mashable: ?The Walking Dead? Celebrates Facebook Milestone With Awesome Poster]

Facebook revealed in a filing with the?Securities and Exchange Commission?on Tuesday that Zuckerberg has "no intention" to sell any of his Facebook shares for at least the next year.

"Mark Zuckerberg... has informed us that he has no intention to conduct any sale transactions in our securities for at least 12 months," Facebook noted in the new SEC filing. "Mr. Zuckerberg currently holds in aggregate approximately 444 million shares of Class B common stock as well as 60 million shares of Class B common stock issuable upon the exercise of an option."

[More from Mashable: 12 Things Students Should Never Do on Social Media]

Some Facebook insiders including cofounder Dustin Moskovitz and early investor Peter Thiel have already begun the process of offloading some of their shares in the company, despite the fact that Facebook's stock value has dropped to less than half of its IPO price.

Zuckerberg, for his part, did sell off more than 30 million shares of Facebook stock immediately after the IPO, earning more than $1 billion in the process. But most of that just went to cover his own taxes.

The new self-imposed ban makes a lot of sense. Not only would it be foolish for Zuckerberg to start selling off more shares now, considering how much their value has plummeted, it would also potentially send a bad message to investors that even Facebook's CEO doesn't want to hold onto the stock.

Image courtesy of Flickr, denneyterrio

This story originally published on Mashable here.

Source: http://news.yahoo.com/zuck-wont-sell-facebook-shares-181625138.html

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